- Racing Car Supplies, South Lyon
- Radiator Coolant & Solvents, South Lyon - Engine Coolant
- Radio & Television Repair Shops , South Lyon - TV Repair
- Radio Communications Equipment & Systems , South Lyon
- Range & Oven Repair, Service & Sales, South Lyon
- Raw Products, South Lyon
- Ready Mix Concrete, South Lyon - Concrete Suppliers, Dealers & Company
- Ready Mix Concrete Producers, South Lyon
- Real Estate, South Lyon - Agent, Broker & Companies
- Real Estate & Insurance Schools, South Lyon
- Real Estate Agent - Property Lessors, South Lyon
- Real Estate Appraisers & Consulting Services, South Lyon
- Real Estate Consultants, South Lyon
- Real Estate Developers, South Lyon
- Real Estate Management, South Lyon
- Real Estate Services, South Lyon
- Recreational Good Manufacturers, South Lyon
- Recycling Scrap & Waste Materials, South Lyon - Scrap Metal, etc
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- Reducing Exercise & Weight Control Services, South Lyon
- Refrigeration Repair & Service, South Lyon - Ac, Freezer, Refrigerator Repair
- Rehabilitation Centers, Products & Services, South Lyon
- Rehabilitation Specialists, South Lyon
- Religious Organizations, South Lyon
- Repair Services, South Lyon
- Research & Development Bureaus, South Lyon - Commercial, Economic, Sociological & Educational Research
- Research Services, South Lyon
- Residential, South Lyon
- Residential Apartments, South Lyon
- Residential Architect, South Lyon
- Residential Care Facilities, South Lyon
- Residential Construction Contractors, South Lyon - General Contractors
- Restaurant & Lounge, Bar, Or Pub, South Lyon
- Restaurants/Food & Dining, South Lyon
- Robots & Robotics System, South Lyon
- Roofing Consultants, South Lyon - Roofing Companies
- Roofing Contractors, South Lyon - Roof Repair, Cleaning, Installation & Maintenance - Roofers
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