- Sand Gravel & Aggregate, Vassar
- Sandwich Shop Restaurants, Vassar
- Scrap & Waste Materials, Vassar
- Screen Printing, Vassar
- Secondary Schools, Vassar
- Security & Surveillance System & Equipment, Vassar
- Senior Citizens Service & Health Organizations, Vassar
- Sharpening Service, Vassar
- Shopping & Shopping Services, Vassar
- Snow Removal Services, Vassar - Snow Plow Service
- Social Services & Welfare, Vassar
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- Sod & Sodding Service, Vassar
- Special Dies Tools Jigs & Fixtures Manufacturers, Vassar
- Special Events & Party Supply Rental, Vassar
- Specialty Stores, Vassar
- Sporting Goods Equipment Rental, Vassar
- Sporting Goods Stores, Vassar
- Sprinkler System Contractors, Vassar - Garden & Lawn Sprinkler System Installation & Repair
- Stamp Collecting & Coin Dealers , Vassar
- Steel & Metal Goods, Vassar - Steel Distributors
- Stoves & Furnace Equipment, Vassar - Fittings & Repair Parts
- Surveyor Services, Vassar - Surveying Service
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