- Obstetricians & Gynecologists, Houghton Lake - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Oil Change & Lubrication, Houghton Lake - Auto Oil & Quick Lube
- Optometrists, Houghton Lake - Eye Doctors, Physicians & Surgeons (Optometry)
- Ornamental Nursery, Houghton Lake
- Ornamental Nursery Services, Houghton Lake
- Orthodontist, Houghton Lake - Teeth Straightening, Invisalign & Dental Braces
- Orthopedic & Prosthetic Appliances & Shoes, Houghton Lake - Orthopedic Shoes
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- Orthotics and Prosthetics, Houghton Lake
- Other Building Materials & Supplies, Houghton Lake
- Other Lodging, Houghton Lake
- Outboard Motors Parts & Repair, Houghton Lake
- Outdoor & Lawn & Garden Equipment Repair & Service, Houghton Lake
- Outdoor Furniture & Patio Furniture, Houghton Lake - Garden Furniture Stores
- Oxygen & Respiratory Equipment & Supplies, Houghton Lake - Oxygen Concentrator, Tank, Machine, etc
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