- Salvage Yards, Junk Yards & Wrecker Service, Grand Ledge
- Sand Gravel & Aggregate, Grand Ledge
- Sandwich Shop Restaurants, Grand Ledge
- Satellite Dish Antennas & Equipment Dealers, Grand Ledge
- Scaffolding & Aerial Lifts, Grand Ledge
- Scrap & Waste Materials, Grand Ledge
- Screen Printing, Grand Ledge
- Secondary Schools, Grand Ledge
- Security Brokers & Dealers, Grand Ledge
- Senior Citizens Service & Health Organizations, Grand Ledge
- Sewer & Drain Cleaning & Repair, Grand Ledge - Drain Cleaner & Installation Services
- Shopping & Shopping Services, Grand Ledge
- Siding Contractors, Grand Ledge - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
- Sign Hanging & Installation Service, Grand Ledge - Signs Erectors & Hangers
- Signs, Grand Ledge
- Sleep Disorders Treatment & Information Centers, Grand Ledge
- Snacks & Desserts, Grand Ledge
- Snow Removal Services, Grand Ledge - Snow Plow Service
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- Social Clubs & Organizations, Grand Ledge
- Social Services & Welfare, Grand Ledge
- Social Workers & Services, Grand Ledge
- Societies & Foundation Associations, Grand Ledge
- Sound Systems, Microphones & Equipment, Grand Ledge
- Special Education & Care, Grand Ledge
- Specialty Animal Services, Grand Ledge
- Specialty Stores, Grand Ledge
- Speech & Hearing Specialists, Grand Ledge
- Sporting Goods Stores, Grand Ledge
- Sports & Recreational Services, Grand Ledge
- State Government, Grand Ledge
- Steel Manufacturers, Grand Ledge
- Stocks & Bond Brokers, Grand Ledge
- Stoves & Furnace Equipment, Grand Ledge - Fittings & Repair Parts
- Submarine Sandwich Restaurants, Grand Ledge
- Surveying Engineer, Grand Ledge
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