- Safety Equipment & Supplies, Sanford
- Sand Gravel & Aggregate, Sanford
- Sandwich Shop Restaurants, Sanford
- Satellite Dish Antennas & Equipment Dealers, Sanford
- Secondary Schools, Sanford
- Senior Citizens Information & Services, Sanford
- Senior Citizens Service & Health Organizations, Sanford
- Septic Tank Installation & Repair, Sanford - Septic Systems
- Septic Tank Pumping & Cleaning, Sanford - Septic Systems
- Septic Tanks & Septic Systems Contractors, Sanford - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Septic Tanks & Systems Contractors & Designers, Sanford
- Shopping & Shopping Services, Sanford
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- Siding Contractors, Sanford - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
- Siding Materials, Sanford
- Snacks & Desserts, Sanford
- Social Services & Welfare, Sanford
- Sound Systems, Microphones & Equipment, Sanford
- Special Events & Party Supply Rental, Sanford
- Specialty Stores, Sanford
- Sporting Goods Equipment Rental, Sanford
- Stamp Collecting & Coin Dealers , Sanford
- State Government, Sanford
- Stereo, Audio & Video Equipment Dealers & Stores, Sanford
- Stoves & Furnace Equipment, Sanford - Fittings & Repair Parts
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