- Sandwich Shop Restaurants, Sandusky
- Scrap & Waste Materials, Sandusky
- Secondary Schools, Sandusky
- Security Alarm Systems - Home & Business, Sandusky
- Security Brokers & Dealers, Sandusky
- Security Control Systems & Monitoring, Sandusky - Polygraph, Lie Detector, CCTV, Fire Sensor Equipment, Etc
- Security Services, Sandusky
- Senior Citizens Housing, Sandusky
- Septic Tank Installation & Repair, Sandusky - Septic Systems
- Septic Tank Pumping & Cleaning, Sandusky - Septic Systems
- Septic Tanks & Septic Systems Contractors, Sandusky - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Sharpening Service, Sandusky
- Sheriff's Department, Sandusky
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- Shopping & Shopping Services, Sandusky
- Signs, Sandusky
- Snow Removal Equipment Repair & Service, Sandusky
- Snowmobile Dealers, Sandusky - Parts, Gear, Clothing & Accessories
- Social Services & Welfare, Sandusky
- Specialty Stores, Sandusky
- Staffing & Support Services, Sandusky
- State Government, Sandusky
- Steel & Metal Goods, Sandusky - Steel Distributors
- Stocks & Bond Brokers, Sandusky
- Sugar Refiners, Sandusky
- Surveyor Services, Sandusky - Surveying Service
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