- Sandwich Shop Restaurants, Saint Louis
- Satellite Dish Antennas & Equipment Dealers, Saint Louis
- Savings & Loan Associations, Saint Louis
- Savings Banks, Saint Louis
- Secondary Schools, Saint Louis
- Security Brokers & Dealers, Saint Louis
- Seed & Grain Cleaning, Saint Louis
- Seed & Grain Cleaning Equipment, Saint Louis
- Senior Citizens Service & Health Organizations, Saint Louis
- Sewing Machines, Equipment & Supplies, Saint Louis
- Ship & Boat Building & Repairing, Saint Louis
- Shooting & Target Ranges, Saint Louis
- Shopping & Shopping Services, Saint Louis
- Small Appliances, Saint Louis
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- Snacks & Desserts, Saint Louis
- Social Services & Welfare, Saint Louis
- Societies & Foundation Associations, Saint Louis
- Special Dies Tools Jigs & Fixtures Manufacturers, Saint Louis
- Special Needs Transportation, Saint Louis
- Specialty Animal Services, Saint Louis
- Specialty Stores, Saint Louis
- State Government, Saint Louis
- Steak House Restaurants, Saint Louis
- Stock & Bond Brokers & Dealers, Saint Louis
- Stocks & Bond Brokers, Saint Louis
- Stoves & Furnace Equipment, Saint Louis - Fittings & Repair Parts
- Substance Abuse Clinics, Saint Louis - Alcoholism, Addiction & Drug Abuse Treatment Centers
- Swimming Pools, Saint Louis
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