- Safety Equipment & Supplies, Edwardsburg
- Sand Gravel & Aggregate, Edwardsburg
- Sand Vehicles, Edwardsburg
- Sandwich Shop Restaurants, Edwardsburg
- Sawmill & Planing Mills, Edwardsburg
- Sawmill Supplies & Equipment Repair, Edwardsburg
- Scrap & Waste Materials, Edwardsburg
- Secondary Schools, Edwardsburg
- Security Brokers & Dealers, Edwardsburg
- Security Guard & Patrol Service, Edwardsburg - Bodyguard, Guard Dogs, Etc
- Security Services, Edwardsburg
- Septic Tank Installation & Repair, Edwardsburg - Septic Systems
- Septic Tank Pumping & Cleaning, Edwardsburg - Septic Systems
- Septic Tanks & Septic Systems Contractors, Edwardsburg - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Sewing & Yarn Stores & Supplies, Edwardsburg
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- Sharpening Service, Edwardsburg
- Sheet Metal, Edwardsburg
- Sheet Metal Contractors, Edwardsburg - Sheet Metal Fabrication
- Sheet Metal Fabricators & Ductwork Contractors, Edwardsburg
- Sheet Metal Work Industrial Manufacturers, Edwardsburg
- Sheriff's Department, Edwardsburg
- Shopping & Shopping Services, Edwardsburg
- Signs, Edwardsburg
- Social Services & Welfare, Edwardsburg
- Societies & Foundation Associations, Edwardsburg
- Specialty Animal Services, Edwardsburg
- Specialty Stores, Edwardsburg
- State Government, Edwardsburg
- Stocks & Bond Brokers, Edwardsburg
- Stoves & Furnace Equipment, Edwardsburg - Fittings & Repair Parts
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